Whitening + anti-inflammatory, tetrahydrocurcumin, you need to understand this ingredient

Whitening + anti-inflammatory, tetrahydrocurcumin, you need to understand this ingredient

The weather is getting warmer and the grass is growing. Some people show their waists on the beach, some people wear jackets under the air conditioner, and some people are armed to the teeth in order to ride the whitening road. Umbrella and sunscreen are the basic standard, tranexamic acid, arbutin, 377, aa2g, niacinamide, and vitamin C raw materials are readily available.

In addition to the well-known ingredients above, there is also an overlooked whitening ingredient: tetrahydrocurcumin.

Sources of Tetrahydrocurcumin

Although the name contains the word ginger, this product is not the ginger we usually eat, but the polyphenolic compounds extracted from the rhizome of turmeric.

Like ginger, turmeric is a typical herb and belongs to the ginger family. Turmeric is a common medicinal material in the Indian medical book “Ayurveda” and traditional Chinese medicine. It has medicinal values ​​of hemostasis, anti-inflammatory and antibacterial. It is often used to inhibit joint pain and externally applied to wounds. It is the most extensive spectrum of Ayurvedic medicine. the panacea.

In fact, many people have also eaten turmeric. For example, the yellowish color in curry rice comes from turmeric. In addition to eating, turmeric has also been found to be a good coloring tool.

In 1842, Vogel et al. isolated bright yellow curcuminoids from turmeric, and then in 1910, V.Lampe and J.Milobedeska further determined the structure of tetrahydrocurcumin. The clinical experiments and research papers of tetrahydrocurcumin were published, mainly focusing on the medicinal value of turmeric: anti-oxidation, anti-inflammatory, anti-cancer and anti-cancer, anti-cardiovascular diseases, etc.

Next, let’s talk about its application in skin care. In the field of daily chemicals, everyone has also fully studied it. When the purity of tetrahydrocurcumin is very high, it will appear as a colorless and odorless white powder. INCI name: Turmeric Extract.

The efficacy of tetrahydrocurcumin

Until now, Indians used turmeric mud on the skin of the bride and groom before their wedding to make their skin soft and smooth.


As mentioned in an article in aogubio before, if you want to whiten, there are generally three ways:

  1. Inhibit the activity of tyrosinase;
  2. Inhibit the factors that cause skin darkening;
  3. Speed ​​up the metabolism of dark skin. In vitro experimental studies have shown that tetrahydrocurcumin can effectively inhibit the activity of tyrosinase, inhibit the production of melanin, and brighten the skin tone.

A foreign study randomly conducted a double-blind placebo-controlled trial on 50 subjects, and the researchers found that in a whitening formula, a cream with 0.25% THC was more effective than 4% hydroquinone (a prohibited skin depigmentation in cosmetics). agent) creams are more effective and safer.


Inflammation of the skin is a complex process. The anti-inflammatory effect of tetrahydrocurcumin is through the inhibition of major inflammatory mediators such as cyclooxygenase, lipoxygenase, interferon, transcription factor and nuclear transcription factor (NF-KB), etc. Inhibition of cyclooxygenase, collagenase and hyaluronidase can reduce skin inflammation including the formation of erythema on the one hand, and can reduce wrinkles and maintain skin elasticity and anti-aging on the other hand.


According to a study by a well-known American journal (J. Am. Chem. Soc.), the antioxidant capacity of natural curcumin is 2.33 times that of bioflavonoids, 1.6 times that of vitamin E and 2.75 times that of vitamin C.

Because curcumin molecule has a variety of antioxidant functional groups: polyphenol, carbon-carbon double bond, ß-diketone, this chemical structure makes it have strong antioxidant activity, scavenging superoxide and peroxide ability. On the one hand, it can remove the generated free radicals, and on the other hand, it can inhibit the further generation of free radicals and break the chain reaction of free radicals. This dual effect can enable skin cells to resist UV damage and maintain skin health.

Recipe Recommendations for Tetrahydrocurcumin

Although tetrahydrocurcumin is very effective, it also has many disadvantages, such as poor water solubility and instability under light conditions. And it is not the all-around king, and it needs to fully cooperate with “teammates” to improve the absorption rate of the human body. Common “teammates”: lecithin, piperine and other plant essential oils.

When adding the formula, it is also necessary to dissolve it with a solvent. When adding it to the formula at low temperature, the formula recommends that the pH is weakly acidic, preferably between 5.0 and 6.5, and is stable in a 0.1M phosphate buffer system.

Summary of Tetrahydrocurcumin

Although there is no such thing as a panacea, as long as we learn from each other’s strengths, we can exert its ideal effect. Due to its unique chemical structure, tetrahydrocurcumin has powerful antioxidant, anti-inflammatory, whitening and brightening effects. At the same time, how to improve the skin’s absorption rate and stably add it to cosmetics under the premise of ensuring efficacy is an opportunity and challenge for formulators.

XI’AN AOGU BIOTECH CO.,LTD is devoted into the research and innovation in natural nutritional supplements ingredients. Our own factory and lab with the strict quality control system to ensure quality stability and real price of Tetrahydrocurcumin. At the same time, we have our own source for the raw material to make sure the production ability.