Diosmin

Name: Diosmin

CAS#: 520-27-4

Botanical Source: Immature bitter orange

Specification: EP, HPLC 90%–98%, Micronized Powder or Granule

Function & Application: Diosmin can protect blood vessel, enhance blood vessel tension, reduce capillary permeability, strengthen its resistance, invrease lymphatic drainage speed and its effect of contraction.

Name: Diosmin
CAS#: 520-27-4
Botanical Source: Immature bitter orange
Specification: EP, HPLC 90%–98%, Micronized Powder or Granule
Function & Application: Diosmin can protect blood vessel, enhance blood vessel tension, reduce capillary permeability, strengthen its resistance, invrease lymphatic drainage speed and its effect of contraction.

TEST ITEM STANDARD RESULT
Appearance Greyish-yellow or light yellow hygroscopic powder Complies (Visual)
Melting point 277℃-278℃ Complies(Melting point apparatus)
Identification (a)(b) Must Positive Complies
Solubility
 – in water Insoluble Complies
 – in dimethyl sulfoxide Soluble Complies
– alcohol Insoluble
– dilute solutions of alkali hydroxides Soluble
Residue on ignition ≤0.5% Complies
Mesh size 100% pass 80 mesh/2000 mesh Complies
Iodine ≤0.1% Complies (Potentiostat)
Related substances
– acetoisovanillone ≤0.5% Complies (HPLC)
– hesperidin ≤4.0% Complies (HPLC)
– isorhoifolin ≤3.0% Complies (HPLC)
– 6-iododiosmin ≤0.6% Complies (HPLC)
– linarin ≤3.0% Complies (HPLC)
– diosmetin ≤2.0% Complies (HPLC)
– unspecified impurities ≤0.4% Complies (HPLC)
– total ≤8.5% Complies (HPLC)
Heavy metals 90%—102%  Complies (HPLC)
Water ≤6.0% Complies (K.F)
Residual solvents
– methanol ≤3000ppm Complies (HPGC)
– acetic acid ≤5000ppm Complies (HPGC)
– pyridine ≤200ppm Complies (HPGC)
Assay
MICROBIOLOGICAL TEST STANDARD RESULT
Total microbial count ≤1000cfu/g Complies
Yeast & mold ≤100cfu/g Complies
E.Coli Negative Negative
Salmonella Negative Negative

GMO STATEMENT

We hereby declare that, to the best of our knowledge, this product was not produced from or with GMO plant material.

BY PRODUCTS & IMPURITIES STATEMENT

We hereby declare that, to the best of our knowledge, this product does not contain and was not manufactured with any of the following substances:

Parabens

Phthalates

Volatile Organic Compounds (VOC)

Solvents and Residual Solvents

GLUTEN FREE STATEMENT

We hereby declare that, to the best of our knowledge, this product is gluten-free and was not manufactured with any ingredients containing gluten.

(BSE)/ (TSE) STATEMENT

We hereby confirm that, to the best of our knowledge, this product is free of BSE/TSE.

CRUELTY-FREE STATEMENT

We hereby declare that, to the best of our knowledge, this product has not been tested on animals.

KOSHER STATEMENT

We hereby confirm that this product has been certified to Kosher standards.

VEGAN STATEMENT

We hereby confirm that this product has been certified to Vegan standards.

FOOD ALLERGEN INFORMATION

Component Present in the product
Peanuts (and/or derivatives,) e.g., protein oil No
Tree Nuts (and/or derivatives) No
Seeds (Mustard, Sesame) (and/or derivatives) No
Wheat, Barley, Rye, Oats, Spelt, Kamut or their hybrids No
Gluten No
Soybeans (and/or derivatives) No
Dairy (including lactose) or Eggs No
Fish or their products No
Shellfish or their products No
Celery (and/or derivatives) No
Lupin (and/or derivatives) No
Sulphites (and derivatives) (added or > 10 ppm) No